“This gene-to-molecule research is crucial for discovery in Alzheimer’s disease. It offers fresh perspectives on how genetic risk factors, such as APOE, influence metabolism and perhaps disease ...

A Stanford-led team discovered a new ketosis pathway involving BHB-amino acids, shedding light on its effects like appetite ...

Mice inoculated with the human gut microbiome had the highest fasting glucose, highest triglyceride levels, lowest ...

Recent findings suggest that microbiota-derived metabolites may modulate higher brain functions, including mood and cognition, opening new avenues for research. The brain influences gut function ...

These metabolites are powerful signaling molecules that have profound effects on the proteome and protein quality control in the brain. Scientists, working in mouse models of Alzheimer's disease ...

Metabolic dysfunctions are one of the major contributors to the development of Alzheimer’s Disease (AD). They are one of the main causes of the inflammatory ...

The study found changes to proteins in the blood—at 57, 70, and 78 years of age—marked three distinct phases of brain aging.

Environ Health Perspect 2011; 119(2): 219-24. Govindaraju V, Young K, Maudsley AA. 2000. Proton NMR Chemical Shifts and Coupling Constants for Brain Metabolites. NMR Biomed 13(3): 129-153. Kaiser LG, ...

A Stanford-led team has discovered a new ketosis pathway involving BHB-amino acids, shedding light on its effects like ...

Research at the Buck Institute shows that ketone bodies can best be understood as powerful signaling metabolites affecting brain function in aging and Alzheimer’s disease. A new study ...