Scientists have made a major discovery about how cells repair broken strands of DNA that could have huge implications for the treatment of cancer. Their study, published in Nature today (Wednesday), ...

Beyond its role in meiosis, recombination is important to somatic cells in eukaryotes because it can be used to help repair broken DNA, even when the break involves both strands of the double helix.

Researchers from the Biotechnology Center (BIOTEC) of the Dresden University of Technology have now answered the ...

The natural ends of chromosomes appear alarmingly like broken DNA, much as a snapped spaghetti strand is difficult to distinguish from its intact counterparts. Yet every cell in our bodies must ...

DNA can be damaged in various ways by different things, such as exposure to UV rays, pollution, or chemotherapy. When both strands of the double-stranded DNA molecule are broken, it is known as a ...

SWSAP1-SWS1 helps repair broken DNA by bringing a suite of repair proteins to the site of damage and keeping them attached and moving along the DNA to conduct their repairs. BRCA2 removes coatings ...

Researchers found that mutations to the retinoblastoma gene or RB1 – which are found in many cancers – prevent the effective fixing of broken DNA strands. This results in chromosome abnormalities ...

These proteins organize themselves into “hubs,” where multiple damaged DNA regions come together. These hubs are similar to “repair cafés,” where people gather to fix broken items.