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登上《细胞-代谢》封面!马学磊/石虎兵/雷震团队首次发现PD-L1乳酸 ...
▎药明康德内容团队编辑 结直肠癌(CRC)是全球第三大常见癌症,其死亡率不断上升。美国FDA已批准使用免疫检查点抑制剂(ICI)治疗CRC,包括PD-1抑制剂,然而超过85%具有pMMR/MSS特征的患者几乎无法从中受益。癌细胞具有高度的代谢状态, ...
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