This represents a conceptual breakthrough.Not only does it offer targets for therapy for several diseases, but we are adding ...

Chromatin immunoprecipitation (ChIP) is a technique for identifying and characterizing elements in protein-DNA interactions involved in gene regulation or chromatin organization. Microarray ...

A new study led by Prof. Yosef Buganim from the Hebrew University of Jerusalem and Dr. Abdenour Soufi from the University of ...

The proper folding of the chromatin structure plays a crucial role in the regulation of genomic DNA functions, its disruption leading to various diseases. Therefore, understanding the chromatin ...

Caltech researchers have developed a new method to map the positions of hundreds of DNA-associated proteins within cell ...

The Whitehouse lab is broadly interested in understanding how chromatin functions in the regulation of cellular processes such as DNA replication, gene transcription and epigenetics. We focus on ...

One key discovery was the influence of chromatin topology, which refers to the folding and looping of DNA within the nucleus. These structures guide TFs along DNA pathways or concentrate them at ...

Chromatin is a combination of DNA and proteins that makes up the chromosomes in the cells of humans and other higher ...

Nearly half the world's population lives in regions where malaria is endemic, with the parasite Plasmodium falciparum ...

Epigenetic regulation relies on the dynamic modification of the two building blocks of chromatin: DNA and histone packaging proteins, to establish and maintain cell identity and fate. We develop and ...