(B) Acute effects of DNA damage on cell cycle progression ... include permanent changes in the DNA sequence (point mutations affecting single genes or chromosome aberrations that may involve ...
transcription and DNA damage repair. Through whole genome sequencing and analysis of thousands of tumor samples, the researchers detected multiple structural variations, including nucleotide ...
The new blood-based test—called AR-ctDETECT—is designed to detect and analyze small fragments of tumor-derived DNA in the ...
RNA polymerase enzymes read the DNA sequence and synthesize messenger RNA (mRNA ... These mechanisms can detect and correct different types of DNA damage, such as base mismatches, single-strand breaks ...
The study demonstrates how these proteins collaborate in so-called "hubs" to repair DNA damage. This knowledge offers opportunities to improve cancer therapies and other treatments where DNA ...
The input of the DeepTXsolver is the parameters of the mechanism model, and the output is the corresponding stationary distribution solution of the model. The input to the DeepTXinferrer is the ...
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Extracellular vesicle DNA regulates immune responses and suppresses liver metastasisThe study highlights how EV-DNA packaging influences immune responses and its promise as a biomarker for assessing colorectal ...
Optical phenotypes are typically inaccessible for sequencing-based approaches based ... of 292 mutations in 27 genes critical ...
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