Over the past decade, there has been an explosion in the identification of the number and variety of post-translational modifications that occur on histone tails, including acetylation ...

Nucleosomes lacking H2B and H3 tails exhibit weakened interactions between histone tails and nucleosomal DNA, leading to less stable nucleosome structure.

The basic organizational unit of the genome is a nucleosome, which is a short segment of DNA wound around a complex of eight histone subunits. Each of these histones has a tail region which can be ...