Scientists identified early genetic mutations in healthy women’s breast cells that may lead to breast cancer, particularly in ...

The luminal cells express abundant CK8, CK18, AR, Nkx3.1, PSA, and PSAP; and lack nuclear p63, CK5, CK14, and most integrins. The apoptosis regulator BCL-2 is highly expressed in basal cells and ...

The formation of blood vessels is a complex process involving the interplay of proteins and mechanical forces. In two studies ...

More information: Luminal breast epithelial cells of BRCA1 or BRCA2 mutation carriers and non-carriers harbor common breast cancer copy number alterations, Nature Genetics (2024). DOI: 10.1038 ...

Researchers have uncovered new mechanisms in blood vessel formation, showing how cells interact during lumen formation and ...

City of Hope® Research Spotlight offers a glimpse at groundbreaking scientific and clinical discoveries advancing lifesaving ...

Cells also monitor the survival factors and negative ... One side of this tissue faces the lumen, where it comes in contact with digested food. The other side attaches to a specialized ECM support ...

Blood vessels are vital for our body, transporting essential nutrients and oxygen through circulating blood. During vessel ...

With approval, the company can begin commercializing the device in the U.S. in 2025.

While genetic alterations were detected at very low levels in most of the women studied, they were only detected in the luminal cells that line the lobules and ducts where milk flows through the ...