To infer gene regulatory networks (GRNs) of mixed populations in scRNA-seq data, the research team utilized the mixture ...

Diseases marked by progressive deterioration of the brain—neurodegeneration—have proven challenging to understand and treat.

In this feature, we explore the impacts of technical variability in single-cell experiments and how standardisation might be ...

Giovanna Prout from Scale Biosciences discusses the inspiration for and results of the company’s ambitious single-cell ...

We offer a range of services, including single cell RNA sequencing and spatial transcriptomics. Our facility is equipped with state-of-art instruments, including the 10X Genomics Chromium X which ...

Use precise geolocation data and actively scan device characteristics for identification. This is done to store and access ...

RiboD-PETRI, a cost-effective, equipment-free plate-based scRNA-seq technique that integrates a unique bacterial rRNA depletion protocol, significantly enhancing mRNA detection rate and revealing ...

Computational biologists from the National University of Singapore (NUS) have uncovered how RNA splicing—a crucial process ...

RNA sequencing refers to techniques used to determine the sequence of RNA molecules. It includes high-throughput shotgun sequencing of cDNA molecules obtained by reverse transcription from RNA ...

Then, scientists can analyze the composition of RNA molecules that contain codes for building new proteins. "However, typical single-cell sequencing experiments use what is called short-read ...

This important discovery helps explain how individuals' genetic differences contribute to their predisposition to complex diseases such as systemic lupus erythematosus (SLE) and Graves' disease (GD).