The 2009 ESBOC meeting covered advances in synthesis, biosynthesis and biological mechanisms of vitamins and cofactors. Recent exciting developments in the field include the development of 'green ...

Coenzyme A (CoA) is an essential cofactor in all living cells. CoA and its thioesters participate in diverse anabolic and catabolic pathways, allosteric interactions, biosynthesis of neurotransmitters ...

Oxygenases have long been thought to require a cofactor for catalysis. The structure of a vancomycin biosynthetic enzyme in complex with a substrate analog, and with molecular oxygen bound in its ...

Research conducted at the State University of Campinas (UNICAMP) in São Paulo state, Brazil, shows that heat treatment of pea protein and addition of guarana extract result in a compound with ...

However, the inhibition of the mevalonate pathway decreases the formation of coenzyme Q10 (CoQ10) within the body. It has been a long-standing theory that statin-associated muscle pain (myalgia ...

Vitamin B6 plays the role of coenzyme for tryptophan. Iron is a cofactor for aromatic L-amino acid decarboxylase that participates in the production of serotonin. If either of these is low ...

Impact and progress Frontiers' impact Progress Report 2022 All progress reports ...

Creative Commons (CC): This is a Creative Commons license. Attribution (BY): Credit must be given to the creator. Prokaryotes and eukaryotes secrete extracellular vesicles (EVs) into the surrounding ...

AKR1B10 encodes proteins that catalyze the reduction of aldehydes, ketones, and quinones. It interacts with heat- shock protein 90α and regulates lipid synthesis via acetyl coenzyme A carboxylase α ...

Department of Pharmaceutical Sciences, University of Illinois Chicago, Chicago, Illinois 60607, United States Department of Chemistry, University of Illinois Chicago, Chicago, Illinois 60607, United ...