The biological effects of p53 pathway variants at the molecular level in primary cells or in vivo still need to be determined. The design of genetically engineered mice using knock-in and knockout ...

Overall, this fundamental study identified a novel role of NOLC1 in regulating p53 nuclear transcriptional activity and p53-mediated ferroptosis in gastric cancer. The evidence supporting the ...

Westlake University in China and the California Institute of Technology have designed a protein-based system inside living ...

Tests of fellowship with God; reality and remedy of sin; danger of antichrists; loving one another. But whoso keepeth His Word, in him verily is the love of God perfected (1 John 2:5). The Lord warns: ...

Polo-like kinase 1 (PLK1), highly expressed in various primary tumor tissues including glioblastomas, thyroid cancer, head and neck squamous cell carcinoma, and acute myeloid leukemia, has become a ...

eLife is a non-profit organisation inspired by research funders and led by scientists. Our mission is to help scientists accelerate discovery by operating a platform for research communication that ...

Dis new pathway go allow migrants and dia families to come live permanently for Australia. Di National Innovation visa dey replace di Global Talent visa wey end for 6 December. According to di ...

There is evidence that lower doses may be equally effective, especially in patients with less severe edema. [10] If beneficial, neurological improvement can be expected within 48 h with this ...