Rous sarcoma virus - Wikipedia
Rous sarcoma virus (RSV) (/ r aʊ s /) is a retrovirus and is the first oncovirus to have been described. It causes sarcoma in chickens. As with all retroviruses, it reverse transcribes its RNA genome into cDNA before integration into the host DNA.
How a Chicken Helped Solve the Mystery of Cancer
2017年12月27日 · The rediscovery of Dr. Rous’s work in the 1960s led researchers to ask what it was about the virus that enabled it to cause cancer. From early experiments, they knew that every cell in the chicken tumor contained the Rous sarcoma virus.
Rous Sarcoma Virus - an overview | ScienceDirect Topics
Rous sarcoma virus (RSV) was isolated by Peyton Rous in 1911 in New York and shown to transmit sarcomas through cell-free extracts from a chicken sarcoma. Rous was awarded the Nobel Prize in 1966 for showing that cancer can be transmitted by a virus; this was the beginning of tumor virology.
Rous Sarcoma Virus (RSV) - News-Medical.net
2019年2月26日 · Rous sarcoma virus (RSV) was discovered by Peyton Rous, who published his findings in the Journal of Experimental Medicine, 1911. Credit: Carl Dupont/Shutterstock.com. …
Rous Sarcoma Virus - an overview | ScienceDirect Topics
Based on the early work of Rous on the transmission of sarcoma in fowl, the Rous sarcoma virus (RSV), which carries the v-SRC oncogene, was eventually discovered. 1 The v-SRC oncogene is a truncated, constitutively active form of the wild-type proto-oncogene c-SRC (or “Src”).
The early history of tumor virology: Rous, RIF, and RAV
One hundred years ago Peyton Rous recovered a virus, now known as the Rous sarcoma virus (RSV), from a chicken sarcoma, which reproduced all aspects of the tumor on injection into closely related chickens.
The Structure and Function of the Rous Sarcoma virus RNA ...
Rous sarcoma virus (RSV) is an avian retrovirus originally discovered by Peyton Rous in 1911 as a filterable transmissible agent isolated from a sarcoma of the common fowl [Rous, 1911]. All retroviruses have two copies of a plus strand RNA genome, which is capped and polyadenylated [Beemon et al., 1974; Furuichi et al., 1975].